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霍长虹教授简介

双击自动滚屏 发布时间:2008-03-20

        天然药物化学教研室教授,硕士生导师,副主任。2005年毕业于北京大学获生药学专业博士学位,为第十届中国药学会施维雅青年药物化学奖的获得者,河北医科大学中青年骨干教师。主要研究方向为天然药物化学成分与活性筛选。近年来主持或主研国家863课题、国家和河北省自然科学基金、 国家 博士后科学基金、河北省中医药管理局、教育厅、卫生厅等多项课题。获河北省自然科学二等奖一项,河北省中医药学会科学技术一等奖两项;中国药学会第八届全国青年药学工作者最新科研成果交流会三等奖和北京药学会百奥杯优秀论文一等奖各一项。

  

已在国内外专业期刊上发表科研论文130余篇,其中作为第一作者或通讯作者发表论文40余篇,包括SCI论文30篇:

     [1]    Donggui Yao, Yufang Wang, Changhong Huo*, et al. Study on the metabolites of isoalantolactone in vivo and in vitro by ultra performance liquid chromatography combined with Triple TOF massspectrometry. Food Chemistry, 2017, 214(1):328–338.

     [2]    Donggui Yao, Zhe Li, Changhong Huo*, et al. Identification of in vitro and in vivo metabolites of alantolactone by UPLC-TOF-MS/MS. Journal of Chromatography B, 2016, 1033:250–260.

     [3]    Ying Ge, Yazhen Wang, Pingping Chen, Yufang Wang, Congcong Hou, Yibing Wu, Manli Zhang, Ligeng Li, Changhong Huo*, et al. Polyhydroxytriterpenoids and Phenolic Constituents from Forsythia suspensa (Thunb.) Vahl Leaves. Journal of Agricultural and Food Chemistry, 2016, 64(1):125-131.

     [4]    Qing Zhang, Zhen Lu, Xing Li, Yuan Zheng, Donggui Yao, Yucheng Gu, Changhong Huo*, et al. Triterpenoids and Steroids from the Leaves of Forsythia suspensa. Chemistry of Natural Compounds, 2015, 51(1):178-180.

     [5]    Yibing Wu, Jian Su, Ruixia Guo, Tianku Ren, Manli Zhang, Mei Dong, Francoise Sauriol, Qingwen Shi, Yucheng Gu, Changhong Huo*. Two New Non-Taxoids from Leaves of Taxus cuspidate. Chemistry of Natural Compounds, 2014, 50(4):603-605.

     [6]    Yibing Wu, Yan Yang, Mei Dong, Francoise Sauriol, Qingwen Shi*, Yucheng Gu, Changhong Huo*. A New Taraxastane-Type Triterpene from the Flowers of Inula cappa. Chemistry of Natural Compounds, 2014, 50(5):850-852.

     [7]    Qing Zhang, Zhen Lu, Tiankun Ren, Ying Ge, Yuan Zheng, Donggui Yao, Xiaoji He, Yucheng Gu, Qingwen Shi, Changhong Huo*. Chemical Composition of Achillea alpina. Chemistry of Natural Compounds, 2014, 50(3):534-536.

     [8]    Yibing Wu, Ying Bai, Xiaohan Guo, Jinlong Qi, Mei Dong, Francoise Sauriol, Qingwen Shi, Yucheng Gu, Changhong Huo*. A New Limonoid from Xylocarpus granatum. Chemistry of Natural Compounds, 2014, 50(2): 314-316.

     [9]    Changhong Huo, et al. A new glyceride from the seeds of Xylocarpus granatum. Chemistry of Natural Compounds, 2013, 48(6): 934-937.

  [10]    Chang-Hong Huo, et al. Cytotoxic flavonoids from the flowers of Achillea millefolium. Chemistry of Natural Compounds, 2013, 48(6): 958-962.

  [11]    Qing Zhang, Chenhong Jia, Haiyun Xu, Yufang Wang, Manli Zhang, Changhong Huo*, et al. Chemical Constituents of Plants from the Genus Forsythia. Mini Reviews in Organic Chemistry, 2012, 9(3):303-318.

  [12]    Chang-Hong Huo, et al. Xylocarponoids A and B, Unique 28C skeleton limonoids from Xylocarpus granatum. Tetrahedron Letters, 2010, 51(4):754-757.

  [13]    Changhong Huo, et al. New neolignan glycosides and a new cerebroside from Symplocos caudata. Chemistry of Natural Compounds, 2010, 46(3):343-347.

  [14]    Yong-Ming Zhao, Yu-jin Wang, Mei Dong, Man-Li Zhang, Chang-Hong Huo*, et al. Two new eudesmanes from Inula helenium. Chemistry of Natural Compounds, 2010, 46(3):373-376.

  [15]    Lei Zhao, Chang-Hong Huo*, et al. Chemical Constituents of Plants from the Genus Melia. Chemistry & Biodiversity, 2010, 7(4):839-859.

  [16]    Baowei Yin, Changhong Huo*, et al. Protolimonoids from the seeds of Xylocarpus granatum. Biochemical Systematics and Ecology, 2009, 37(3):218-220.

  [17]    Li-Ru Shen, Mei Dong, Dong Guo, Bao-Wei Yin, Man-Li Zhang, Qing-Wen Shi, Chang-Hong Huo*, et al. Xylomexicanins A and B, New Δ14,15-Mexicanolides from Seeds of the Chinese Mangrove Xylocarpus granatum. Zeitschrift fuer Naturforschung, C, 2009, 64c (1/2):37-42.

  [18]    Li-Ru Shen, Dong Guo, Yue-Mei Yu, Bao-Wei Yin, Lei Zhao, Qing-Wen Shi, Yongli Wang, Chang-Hong Huo*. Chemical Constituents of plants from the Genus Xylocarpus. Chemistry & Biodiversity, 2009, 6(9):1293-1308.

  [19]    Changhong Huo, et al. Neolignan glycosides from Symplocos caudata. Phytochemistry, 2008, 69(3):788-795.

  [20]    Changhong Huo, et al. A new 5,11- Epoxymegastigmane Glucoside from Acanthus ilicifolius. Natural Product Research, 2008, 22(10):896-900.

  [21]    Bao-Wei Yin, Li-Ru Shen, Man-li Zhang, Lei Zhao, Yong-Li Wang, Chang-Hong Huo*, et al. Chemical Constituents of Plants from the Genus Excoecaria. Chemistry & Biodiversity, 2008, 5(11):2356-2371.

  [22]    Changhong Huo, et al. Canataxpropellane, a novel taxane with a unique polycyclic carbon skeleton (tricyclotaxane) from the needles of Taxus canadensis. Tetrahedron Letters, 2007, 48(15):2721-2724.

  [23]    Changhong Huo, et al. Structural determination of a new 2(3®20) abeotaxane with an unusual 13-substitution pattern and a new 6/8/6 -ring taxane from Taxus cuspidata. Magnetic Resonance in Chemistry, 2007, 45(4):527-530.

  [24]    Changhong Huo, et al. Two new taxanes from Taxus canadensis. Biochemical Systematics and Ecology, 2007, 35(12):909-913.

  [25]    Changhong Huo, et al. A new taxol analogue from the leaves of Taxus cuspidata. Biochemical Systematics and Ecology, 2007, 35(10): 704-708.

  [26]    Changhong Huo, et al. A New Metabolite with A New Substituted Pattern from the Seeds of the Chinese Yew, Taxus mairei. Chemistry & Biodiversity, 2007, 4(1):84-88.

  [27]    Changhong Huo, et al. Chemical Constituents of Plants from the Genus Symplocos. Chemistry & Biodiversity, 2007, 4(1):1-11.

  [28]    Liru Shen, Shumin Jin, Baowei Yin, Xiufang Du, Yongli Wang, Changhong Huo*. Chemical Constituents of plants from the Genus Cerbera. Chemistry & Biodiversity, 2007, 4(7):1438-1449.

  [29]    Changhong Huo, et al. Structure elucidation and complete NMR spectral assignments of a new benzoxazolinone glucoside from Acanthus ilicifolius. Magnetic Resonance in Chemistry. 2005, 43(4):343-345.

  [30]    Changhong Huo, et al. Benzoxazinones from Acanthus ilicifolius. Biochemical Systematics and Ecology. 2005, 33(6):643-645.

  [31]    霍长虹,等. 木果楝种子中一个新柠檬苦素类化合物. 中草药, 2010, 41(2):176-178.

  [32]    霍长虹, . 山矾的化学成分研究. 中草药, 2009, 40(7):1039-1042.

  [33]    沈立茹,郭栋,尹宝伟,张青,赵雷,霍长虹*,等. 红树林植物木果楝化学成分的研究. 中草药, 2009, 40(8):1201-1204.

  [34]    霍长虹, . 东北红豆杉针叶中紫杉烷类化学成分的研究. 中草药, 2008, 39(3):347-350.

  [35]    霍长虹, . 天然紫杉烷类化合物的核磁共振氢谱特征. 波谱学杂志, 2007, 24(1):101-118.

  [36]    霍长虹, . 苯骈?f嗪酮类化合物的结构特征和谱学规律. 北京大学学报医学版, 2006, 38(3):321-323.

  [37]    霍长虹, . 红树林植物老鼠?{化学成分的研究. 中国中药杂志, 2006, 31(24):2052-2054.

  [38]    霍长虹, . 老鼠?{化学成分的研究. 中国中药杂志, 2005, 30(10):763-765.

  [39]    霍长虹, . 老鼠?{属植物化学成分及其活性研究进展. 中国海洋药物,2004, 99(3):39-44.

  [40]    霍长虹, . 合欢皮水煎剂催眠作用的药理实验研究. 河北医科大学学报, 2002, (4):216-217.

  [41]    霍长虹,等. 苯乙醇胺类化合物的合成及其支气管扩张活性. 中国药物化学杂志,1999, 9(2):94-97.

  [42]    霍长虹,等. 组合化学中的固相合成法. 中国药物化学杂志,1998, 8(3):228-234.

 

 (最新修改时间:2017年3月20日)